{"id":545112,"date":"2026-08-27T04:39:17","date_gmt":"2026-08-27T02:39:17","guid":{"rendered":"https:\/\/dev.phytocontrol.com\/uncategorized\/anses-opinion-on-spirulina-based-food-supplements\/"},"modified":"2026-09-20T12:57:21","modified_gmt":"2026-09-20T10:57:21","slug":"anses-opinion-on-spirulina-based-food-supplements","status":"publish","type":"post","link":"https:\/\/dev.phytocontrol.com\/en\/regulatory-watch\/anses-opinion-on-spirulina-based-food-supplements\/","title":{"rendered":"ANSES opinion on spirulina-based food supplements"},"content":{"rendered":"<p><img decoding=\"async\" class=\"aligncenter size-full wp-image-4413\" src=\"http:\/\/preprod-phytocontrol.choosit.com\/wp-content\/uploads\/2017\/12\/photo-actu-spiruline-anses.jpg\" alt=\"Spiruline anses\" width=\"400\" height=\"120\" srcset=\"https:\/\/dev.phytocontrol.com\/app\/uploads\/2017\/12\/photo-actu-spiruline-anses.jpg 400w, https:\/\/dev.phytocontrol.com\/app\/uploads\/2017\/12\/photo-actu-spiruline-anses-300x90.jpg 300w, https:\/\/dev.phytocontrol.com\/app\/uploads\/2017\/12\/photo-actu-spiruline-anses-260x78.jpg 260w, https:\/\/dev.phytocontrol.com\/app\/uploads\/2017\/12\/photo-actu-spiruline-anses-50x15.jpg 50w, https:\/\/dev.phytocontrol.com\/app\/uploads\/2017\/12\/photo-actu-spiruline-anses-150x45.jpg 150w\" sizes=\"(max-width: 400px) 100vw, 400px\" \/><\/p>\n<p>&nbsp;<\/p>\n<p>&nbsp;<\/p>\n<p>On 30 November 2017, ANSES published an opinion on the risk to consumers related to the consumption of spirulina-based food supplements.<br \/>\n49 reports of adverse effects potentially linked to the consumption of this type of supplement have been collected as part of the national Nutrivigilance scheme.<br \/>\nSpirulina is a cyanobacterium of the genus <em>Arthrospira<\/em>. It grows on the surface of water and develops naturally in warm (25\u00b0C), alkaline (pH 8-11.5) fresh water, rich in carbonates and bicarbonates but also in nitrates, phosphates and iron.<br \/>\nIt is used in the form of food supplements, as a colouring agent, and also in animal feed.<br \/>\nSpirulina is considered a foodstuff subject to Regulation (EC) No. 396\/2005 on maximum residue levels of pesticides.<br \/>\nThree species of spirulina are authorised in food supplements under the Order of 24 June 2014:<br \/>\n&#8211; <em>Spirulina major<\/em><br \/>\n&#8211; <em>Spirulina maxima<\/em><br \/>\n&#8211; <em>Spirulina platensis<\/em><br \/>\nSpirulina has been produced industrially since the 1980s, and since the 2000s it has been produced using photobioreactors.<br \/>\nIn France, it is sold in powder form or as food supplements, with an intake of 0.25 to 5g of spirulina per day.<\/p>\n<p>Spirulina may contain various contaminants: cyanobacteria of other genera and their toxins, heavy metals and other bacterial species.<\/p>\n<p><strong>Cyanotoxins:<\/strong><\/p>\n<p>They are produced by several genera of cyanobacteria and are classified into three categories: hepatotoxins (microcystins), neurotoxins (anatoxins, saxitoxins and BMAA) and dermatotoxins.<\/p>\n<p><strong>Cyanobacteria producing cyanotoxins:<\/strong><\/p>\n<p>Several publications have reported the presence of toxic cyanobacteria (<em>Anabaena sp., Anabaenopsis sp., Phormidium sp., Oscillatoria sp., Synechococcus sp.<\/em>), associated with the presence of cyanotoxins (<em>anatoxin-A, microcystins<\/em>).<\/p>\n<p><strong>Other bacteria (non-cyanobacteria):<\/strong><\/p>\n<p>Spirulina production conditions, at a pH of around 10, reduce the development of pathogenic microorganisms (<em>Listeria, Salmonella, coliforms<\/em>\u2026).<br \/>\nHowever, during harvesting, washing, drying, storage, or packaging, and depending on hygiene practices and the water used, contamination can occur.<\/p>\n<p><strong>Contamination by trace metal elements:<\/strong><\/p>\n<p>The metal content of spirulina is directly related to water quality.<br \/>\nOverall, studies generally show acceptable metal levels, but some analyses have also revealed levels exceeding the limits set in EU food supplement regulations.<\/p>\n<p>Most products containing only spirulina (<em>Arthrospira spp.<\/em>) do not show worrying levels of cyanotoxins; however, the data available in the literature do not rule out the production of hepatotoxic microcystins by <em>Arthrospira spp.<\/em> or contamination by other cyanotoxin-producing cyanobacteria.<br \/>\nBacterial contamination, although rare in finished products, does occur during product handling.<br \/>\nMetal quantities exceeding EU limits or the specifications of the USP Dietary Supplements Compendium have been identified in commercial spirulina samples.<\/p>\n<p>The Expert Committee concluded that, given the risk of contamination by metals and cyanobacteria, it is important to ensure the quality of production water, the selection of the inoculum and control of the various production stages.<br \/>\nIt also recommends the introduction of a threshold for microcystins in food supplements containing spirulina.<\/p>\n<p>Your Phytocontrol laboratory is able to carry out trace metal element analysis in spirulina and spirulina-based food supplements, as well as water quality analyses, under COFRAC accreditation. The parameters concerned can be consulted via our COFRAC technical annexes No. 1-1904 and No. 1-6066 available in your customer area or on the COFRAC website.<\/p>\n<p>Please find enclosed the link to the full ANSES opinion: <a href=\"http:\/\/preprod-phytocontrol.choosit.com\/wp-content\/uploads\/2017\/12\/AVIS-de-lAnses-spiruline.pdf\">ANSES opinion on spirulina<\/a><\/p>\n","protected":false},"excerpt":{"rendered":"<p>&nbsp; &nbsp; On 30 November 2017, ANSES published an opinion on the risk to consumers&hellip;<\/p>\n","protected":false},"author":8,"featured_media":11382,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"gallery","meta":{"_acf_changed":false,"footnotes":""},"categories":[181],"tags":[],"class_list":["post-545112","post","type-post","status-publish","format-gallery","has-post-thumbnail","hentry","category-regulatory-watch","post_format-post-format-gallery"],"acf":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO Premium plugin v28.4 (Yoast SEO v28.5) - 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